Drive from Panama City through the crater landscapes of El Valle, the coffee highlands of Boquete and the heart of the country at your own pace.
Trip code: 1120
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Discover Panama beyond the beaches on a rewarding self-drive journey through vibrant cities, volcanic valleys and cool mountain country. Begin in Panama City with time for the Canal and Casco Viejo, continue to El Valle de Antón inside an ancient volcanic crater, and then cross the country to Boquete for coffee estates, cloud forests and highland scenery. Comfortable overnight stops in Santiago and Panama City divide the return drive, while your rental car gives you the freedom to explore at your own pace.
What you’ll do each day, with your included hotel — or upgrade any stay.
Day 1 – Arrival in Panama City
Collect your rental car at Tocumen International Airport and drive to your selected hotel. If your flight arrives late, ask us about collecting the car the following morning. Settle in and enjoy a relaxed first evening.
Day 2 – Canal and Casco Viejo
Visit the Miraflores Locks, explore the Amador Causeway and wander through Casco Viejo’s plazas, cafés and historic streets. Parking in the old quarter can be limited, so hotel parking or a taxi may be more convenient.
Days 1–3 IncludedAdjust the number of nights at this hotel — your itinerary days and price update automatically.
PANAMA CITY 10 days

Economy · Economy
Important information before booking
Driving times are approximate and may vary with traffic, weather and road conditions. Avoid driving after dark, particularly in rural and mountain areas. The rental company’s confirmed inclusions, insurance, mileage policy, deposit and driver requirements take precedence over general package information.